I'm 400 pages in, and the worst possible thing could happen.
Stephenson just starts fucking around with the Geography of Europe. He invents a country in the middle of nowhere. Quicksilver is a book set in a historical setting. It's quite obviously "our world" because it's got bits dealing with the Crusades, the Black Plague, numerous historical figures, etc.
But then, he completely shatters the suspension of disbelief by making up a country. Adding insult to injury, it's not even something "subtle" like having a country's name that might be vaguely pronounceable. Nope, this mythical country's name is Qwghlm. No, that's not spelled wrong. No, there are no vowels in it.
I give up, Neal. You're officially a moron. I read through "Book I" (which is, basically one half of Quicksilver), through around 400 pages or so, and realized I didn't give a wet slap about any of the characters. Not a one. If page 401 told me that a guy from the future came back in time with an M16A2 and slaughtered them all, I would have been OK with that. Now, you just start making up countries with unpronounceable names (although, I'm supposed to believe that's pronounced "taggum"... yeah, whatever) and expect me to just play along.
When I read Stephenson's earlier works, I went on a buying frenzy at the time, snatching up copies of everything I could find, and reading them voraciously.. they were great (although they all seemed to suffer from Stephenson's inability to write a good ending).
Seems now, the entire book is the ending, because the entire volume sucks ass.
I think I finally figured out the "point" of the book. He'll write the three volumes in increasing orders of stupidity and see how sycophantic the book-buying populace... will they keep snatching up his works, even if they amount to nothing more than drunken ravings? Get over yourself, Neal, you're not Jim Morrisson, so the drunken nonsense routine isn't going to play for you nearly as well as it played for him.